INCI Water , Lecithin , Tripeptide10 Citrulline , Carbomer ,Triethanolamine, Caprylyl Glycol
Decorinyl is a synthesized tetrapeptide which mimics the sequences of decorin that bind to collagen fibrils. It has been shown to regulate fibrillogenesis and control fibril growth, improving firmness and elasticity of the skin, ensuring uniformity of fibril diameter and spacing of collagen fibrils. In effect, it replaces the nonfunctional decorin encountered as the skin ages, and also sustains a superior moisture profile. Fibrillogenesis is an essential process in tissue formation, but must be controlled and regulated in order to avoid excessive bundlelike aggregation of collagen. The fibrillogenesis control is the role of decorin, a small leucinerich proteoglycan, which is associated with collagen fibrils at specific binding sites in the protein core, controlling fibril dimensions, the uniformity of their diameter and their regular spacing. Aging skin contains a truncated form of decorin, which lacks binding regions with collagen fibrils, producing a negative effect on the elasticity on the skin. Decorinyl is a mimic peptide of these binding sequences that has been proven to regulate fibrillogenesis, control collagen fibril diameter and increase skin suppleness. Decorinyl has been incorporated into a liposomal system for enhanced penetration, stability and efficacy. It is recommended for cosmetic formulations designed for mature skin where an improvement of suppleness and strength of skin is desired. It may be used in emulsions, gels and other formulations.
Incorporation Decorinyl can be incorporated in the final stage of the manufacturing process, when the temperature has reached 35 - 40C
Care should be taken not to exceed 50C
Appearance Off white to amber liquid suspension pH 5.0- 6.5
Tripeptide10 Citrulline Content 0.2%
Water soluble
Preservative 0.9% Phenoxyethanol
Storage Keep in a cool between 15 and 25C . In order to avoid secondary microbial contamination, following opening, containers should be handled with special care. If stored as recommended, Decorinyl remains stable for at least 12 months. Recommended Usage Rate 0.5% - 5%
INCI Water and Lecithin and Tripeptide10 Citrulline and Carbomer and Triethanolamine and Caprylyl Glycol